Cytotoxic 3,4-Secoapotirucallanes from Aglaia argentea Bark
- 21 April 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 62 (6) , 868-872
- https://doi.org/10.1021/np990013u
Abstract
Nine 3,4-secoapotirucallanes, argentinic acids A-I, were isolated from the bark of Aglaia argentea and transformed to their methyl esters 1-9. The structures were determined by spectral and chemical means. Compounds 1-8 showed moderate cytotoxic activity against KB cells (IC50 1.0-3.5 microg/mL).Keywords
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