Excess IgD Bearing Lymphocytes in Patients with Malignant Melanoma
Open Access
- 1 November 1974
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 30 (5) , 379-381
- https://doi.org/10.1038/bjc.1974.211
Abstract
B lymphocytes from the peripheral blood of 15 melanoma patients and 14 normal adults were studied using immunofluorescence to IgA, IgG, IgD and IgM surface markers. The total number of peripheral blood B lymphocytes was increased in the melanoma patients (1048/mm3) compared with normal controls (504) (P<0·01). The expression of excess IgD bearing lymphocytes in these melanoma patients may reflect a derepression of oncofoetal type.Keywords
This publication has 3 references indexed in Scilit:
- Non-immunoglobulin-bearing‘B’ Lymphocytes in Chronic Lymphatic Leukaemia?British Journal of Haematology, 1973
- IgD on the Surface of Peripheral Blood Lymphocytes of the Human NewbornNature New Biology, 1973
- Evidence for a Tumour-associated Antigen in Human Malignant MelanomaNature, 1973