The Immune Response

Abstract
FROM the early days of immunology, immediate hypersensitivity responses, or the antibody-mediated reactions, were separated from and contrasted with the delayed hypersensitivity response, or the cell-mediated reaction. The reasons for this sharp separation were numerous and cogent. The purpose of this presentation is to point out that the 2 types of reactions have some very important basic similarities. They may both be mediated by antibody, and the observed differences merely reflect the locus of the reaction and the chemical and biologic properties of the antibodies involved. Because an extensive literature has now accumulated in this field, I must be both . . .