The Immune Response
- 21 December 1967
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 277 (25) , 1355-1361
- https://doi.org/10.1056/nejm196712212772507
Abstract
FROM the early days of immunology, immediate hypersensitivity responses, or the antibody-mediated reactions, were separated from and contrasted with the delayed hypersensitivity response, or the cell-mediated reaction. The reasons for this sharp separation were numerous and cogent. The purpose of this presentation is to point out that the 2 types of reactions have some very important basic similarities. They may both be mediated by antibody, and the observed differences merely reflect the locus of the reaction and the chemical and biologic properties of the antibodies involved. Because an extensive literature has now accumulated in this field, I must be both . . .Keywords
This publication has 20 references indexed in Scilit:
- Mechanism of Delayed ReactionsScience, 1967
- THE CARRIAGE OF IMMUNOLOGICAL MEMORY BY SMALL LYMPHOCYTES IN THE RATThe Journal of Experimental Medicine, 1966
- Mechanism of a Reaction in Vitro Associated with Delayed-Type HypersensitivityScience, 1966
- Immunological Studies with Synthetic PolypeptidesPublished by Elsevier ,1966
- Immunogenicity of a Series of α,N-DNP-L-Lysines*Biochemistry, 1965
- Genetic Control in Guinea Pigs of Immune Response to Conjugates of Haptens and Poly-L-LysineScience, 1965
- Immune Response and Mitosis of Human Peripheral Blood Lymphocytes in vitroScience, 1963
- TUBERCULIN-INDUCED MITOSIS IN PERIPHERAL BLOOD LEUCOCYTESThe Lancet, 1963
- Delayed Hypersensitivity to Simple Protein AntigensPublished by Elsevier ,1961
- OCCURRENCE OF DELAYED HYPERSENSITIVITY DURING THE DEVELOPMENT OF ARTHUS TYPE HYPERSENSITIVITYThe Journal of Experimental Medicine, 1958