CYTOSTATIC ACTIVITY OF SOME CANARY ISLANDS SPECIES OFRUTACEAE

1 June 1977

journal article
research article
Published by Georg Thieme Verlag KG in Planta Medica

Vol. 31 (04) , 351-356
https://doi.org/10.1055/s-0028-1097543

Abstract

Eighteen coumarins from different species of Ruta collected in the Canary Islands were tested for cytostatic activity. Rutamarin proved to be strikingly cytotoxic. We tried to establish the structure/activity relationship and also to elucidate the mechanism of the activity of this constituent.

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