Synthesis of Dl-Glutamic Acid from 1,1,1,5-Tetrachloropentane

Abstract
DL-Glutamic acid has been synthesized from 1,1,1,5-tetrachloropentane. The process involves five steps through 1,1,1-trichloro-5-hydroxypentane (92%), 5,5,5-trichlorovaleric acid (94%), 5,5-dichloro-4-pentenoic acid (85%), α-chloroglutaric acid (82%), and DL-glutamic acid (87%). The over-all field from 1,1,1,5-tetrachloropentane to DL-glutamic acid was 52%.

This publication has 3 references indexed in Scilit: