Estimation of alveolar deposition ratio of inhaled radioaerosol.

Publisher Website
Google Scholar
Abstract
The lung retention ratio (LRR) and the alveolar deposition ratio (ALDR) are mandatory to calculate the 3 other indices for quantitatively evaluating mucociliary clearance function of the ciliated airways; the airway deposition ratio (ADR), the airway retention ratio (ARR) and the airway clearance efficiency (ACE). The LRR required 2 h continuous measurement of radioactivity in the thorax and the ALDR a repeat measurement at 24 h after radioaerosol inhalation using the previous method. The 2 h continuous measurement is, however, too long for a clinical examination and the 24 h repeat measurement cumbersome. A way to get the ALDR by calculation without repeating the 24 h measurement and by counting radioactivity for the shortest possible period and yet without sacrificing the visual evaluation by compiling radioaerosol inhalation lung cine-scintigraphy was the purpose of the study. By using the derived formula listed in table 1, the ALDR was calculable. Forced expiratory volume (FEV) in 1 s divided by FEV in per cent (FEV1.0 %), the initial 60 min measurement of radioactivity without repeating 24 h measurement, and smoking history were the minimum requirement to calculate the ALDR. The calculated ALDR appeared reliable enough to estimate the other indices.

This publication has 2 references indexed in Scilit: