Urinary Bladder of Leopard Frogs (Rana pipiens): Effects of Vasotocin, Cyclic AMP, Cyclic GMP and Aldosterone

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Abstract
Isolated urinary bladders of leopard frogs (Rana pipiens) exhibit hydro-osmotic and natriferic responses to vasotocin. Cyclic AMP (but not cyclic GMP) mimics these actions. While the responses to vasotocin are similar to those seen in toads (Bufo marinus), the effects of cyclic AMP are more than twice as great. Aldosterone also increases the short-circuit current across the bladder of the leopard frogs.

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