Functional heterogeneity of osteoclasts: matrix metalloproteinases participate in osteoclastic resorption of calvarial bone but not in resorption of long bone
- 1 July 1999
- journal article
- Published by Wiley in The FASEB Journal
- Vol. 13 (10) , 1219-1230
- https://doi.org/10.1096/fasebj.13.10.1219
Abstract
Data in the literature suggest that site-specific differences exist in the skeleton with respect to digestion of bone by osteoclasts. Therefore, we investigated whether bone resorption by calvarial...Keywords
This publication has 43 references indexed in Scilit:
- Cysteine Proteinases and Matrix Metalloproteinases Play Distinct Roles in the Subosteoclastic Resorption ZoneJournal of Bone and Mineral Research, 1998
- The Migration of Purified Osteoclasts Through Collagen Is Inhibited by Matrix Metalloproteinase InhibitorsJournal of Bone and Mineral Research, 1998
- Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological mediaFEBS Letters, 1996
- Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human OsteoclastsJournal of Biological Chemistry, 1996
- Heterogeneity of the skeleton: Comparison of the trabecular microarchitecture of the spine, the iliac crest, the femur, and the calcaneusJournal of Bone and Mineral Research, 1996
- Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in BoneBiochemical and Biophysical Research Communications, 1995
- Selective inhibition of cysteine proteinases by Z-Phe-AlaCH2F suppresses digestion of collagen by fibroblasts and osteoclastsBiochemical and Biophysical Research Communications, 1991
- Sclerosing bone dysplasias ? a target-site approachSkeletal Radiology, 1991
- The effects of inhibitors of cysteine-proteinases and collagenase on the resorptive activity of isolated osteoclasts☆Bone, 1987
- In vivo and in vitro evidence for the involvement of cysteine proteinases in bone resorptionBiochemical and Biophysical Research Communications, 1984