Studies on the biosynthesis of the mitomycin antibiotics by Streptomyces verticillatus

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Abstract
Biosynthetic studies indicate that the mitomycins are not formed from aromatic precursors, but that [Me-–14C]-L-methionine and [guanido-14C]-L-arginine specifically label peripheral substituents and that glucosamine is probably incorporated intact into a C6-fragment of these antibiotics.