Amitriptyline: A controlled trial in chronic depressive states
- 1 November 1962
- journal article
- Published by Royal College of Psychiatrists in Journal of Mental Science
- Vol. 108 (457) , 859-861
- https://doi.org/10.1192/bjp.108.457.859
Abstract
Amitriptyline hydrochloride is 5–(3 dimethylaminopropylidine)–dibenzo (a,d) (1,4) cycloheptadiene hydrochloride. Structurally it is not related to the hydrazines and is not a monoamine oxidase inhibitor. It bears some resemblance to the phenothiazines and its chemical structure is related to imipramine, in which the central seven numbered ring is azepine, nitrogen replacing the partially unsaturated carbon of the amitriptyline cycloheptadiene ring (Dorfman, 1960; Vernier, 1961).Keywords
This publication has 4 references indexed in Scilit:
- ON THE PARENTERAL USE OF AMITRIPTYLINE (ELAVIL–MERCK): A PRELIMINARY REPORTAmerican Journal of Psychiatry, 1960
- Clinical Experiences with Amitriptyline (Elavil)Psychosomatics, 1960
- Phenelzine (“Nardil”) in the Treatment of Endogenous DepressionJournal of Mental Science, 1960
- Pharmacological Studies with TofrānilCanadian Psychiatric Association Journal, 1959