Sex Hormones and Cancer: Some Effects of the Interplay of Sex Hormones upon the Incidence of Mammary Cancer in Mice

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Abstract
During the last decade many investigators have interested themselves in the study of the hormones of the sex glands and the parts which they play in the physiology of the individual. As often happens when a mass of data is collected by a number of individuals, many divergent and conflicting findings have been published. Out of this mass of data, however, certain principles seem to be generally accepted. Among these is the opinion that the secretions of the various organs do not act independently but are all dependent, one upon the other, and work in a system of checks and balances, any upset in which leads to abnormal physiological function.

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