Rapid progression of lentigo maligna to deeply invasive lentigo maligna melanoma. Report of two cases

Publisher Website
Google Scholar
Abstract
Two patients had lesions of lentigo maligna that evolved into deeply invasive (level 4-5) lentigo maligna melanoma during a relatively short period (2 yr and 4 yr, respectively). In both patients, the clinical impression of lentigo maligna was difficult to confirm by histopathologic analysis until the invasive tumor had developed. Both patients were actively followed up during this period of evolution, with intention of detecting any early changes suggestive of invasive melanoma. Since deep invasion developed despite close clinical supervision, a more aggressive approach to the treatment of lentigo maligna may be warranted.