Discovery of biological networks from diverse functional genomic data
Open Access
- 19 December 2005
- journal article
- Published by Springer Nature in Genome Biology
- Vol. 6 (13) , R114
- https://doi.org/10.1186/gb-2005-6-13-r114
Abstract
We have developed a general probabilistic system for query-based discovery of pathway-specific networks through integration of diverse genome-wide data. This framework was validated by accurately recovering known networks for 31 biological processes in Saccharomyces cerevisiae and experimentally verifying predictions for the process of chromosomal segregation. Our system, bioPIXIE, a public, comprehensive system for integration, analysis, and visualization of biological network predictions for S. cerevisiae, is freely accessible over the worldwide web.Keywords
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