A QUANTITATIVE METHOD FOR CONTINUOUS RECORDING OF SPONTANEOUS ACTIVITY IN SMALL ANIMALS

Abstract
A simple apparatus was devised to record the spontaneous movements of either mice or rats by the use of the photoelectric cage method. Spontaneous activity was measured quantitatively, and continuously. The temporal pattern of drug effects was effectively observed by this method. The activity of mice was not increased by pentylenetetrazol, nikethamide and strychnine in subconvulsive doses, but was increased by metham-phetamine, d-amphetamine, caffeine, ephedrine and morphine.

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