Fatal Poisoning From Sodium Phosphate Enema
- 24 April 1987
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 257 (16) , 2190-2192
- https://doi.org/10.1001/jama.1987.03390160076030
Abstract
An overdose of a common over-the-counter sodium phosphate enema solution was fatal in an infant. The marked hypernatremia, acidemia, hyperphosphatemia, and hypocalcemia observed before death were also produced in a porcine model. A study using pigs showed that the enema solution was lethal if retained in doses above 20 mL/kg, equivalent to four pediatric-sized enemas in a 2-year-old child. Even normal doses of the enema solution caused measurable changes in serum phosphorus and calcium levels. (JAMA1987;257:2190-2192)Keywords
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