Prolonged Apnea Following Succinylcholine in Cancer Patients Receiving AB-132
Open Access
- 1 May 1963
- journal article
- research article
- Published by Wolters Kluwer Health in Anesthesiology
- Vol. 24 (3) , 363-367
- https://doi.org/10.1097/00000542-196305000-00018
Abstract
Prolonged apnea was attributable to the inhibition of the plasma and red blood cell cholinesterases by a antitumor agent, AB-132, which was given to the patients prior to operation. The marked inhibitory effects of AB-132 on blood cholinesterase were demonstrated both in vitro and in four other cancer patients on AB-132 therapy. It is concluded that succinylcholine should not be given during anesthesia to patients receiving this cancer chemotherapeutic agent.Keywords
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