Abstract
STATISTICS on the incidence of cancer in nodular goiter are totally unreliable because all such statistics are based on the selected group of patients whose goiters are removed. Since most patients with small benign nodular goiters are not operated upon and since most patients with true carcinomas sooner or later are operated upon, it is obvious that statistics based on surgical pathology are not representative of the over-all incidence of cancer in nodular goiter.The incidence of nodular goiter varies from place to place and increases with advancing age. In the Great Lakes area, for example, about 5 per cent . . .