Rett Syndrome
- 1 August 1986
- journal article
- research article
- Published by American Medical Association (AMA) in American Journal of Diseases of Children
- Vol. 140 (8) , 761-765
- https://doi.org/10.1001/archpedi.1986.02140220043029
Abstract
• We report 15 cases of Rett syndrome, a slowly progressive disorder that occurs only in girls and is characterized by early deterioration of higher brain function with dementia and autistic behavior, loss of purposeful use of the hands, and deceleration of head growth. Epilepsy, with minor motor seizures being the predominant type, has its onset between 2 and 4 years of age in the majority of cases. Additional features include an extrapyramidal disorder with dystonia and choreoathetosis, and lactic acidemia. A precise biochemical marker of this disorder has not been identified. (AJDC 1986;140:761-765)This publication has 3 references indexed in Scilit:
- Rett syndrome—Clinical studies and pathophysiological considerationBrain & Development, 1984
- A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: Report of 35 casesAnnals of Neurology, 1983
- Slow spike‐wave activity in EEG and associated clinical featuresNeurology, 1977