Structure of cervinomycin, a novel xantone antibiotic active against anaerobe and mycoplasma.
- 1 January 1987
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 40 (3) , 301-308
- https://doi.org/10.7164/antibiotics.40.301
Abstract
The structures of cervinomycins A1 (1) and A2 (2), a potent anti-anaerobic and anti-mycoplasmal antibiotic were investigated by means of recent NMR techniques of O-methyl either (3) and C,O-dimethyl ether (4) obtained by methylation of 2 with CH3I in the presence of Ag2O. The antibiotic 2 possesses a polycyclic structure involving a xanthone skeleton. The structure of 1 was confirmed to be a hydroquinone of 2 from the evidences that oxidation of 1 with Ag2O and acetylation of 1 with (CH3CO)2O in pyridine afforded quantitatively 2 and triacetylcervinomycin A1 (7), respectively.This publication has 3 references indexed in Scilit:
- Cervinomycin A1 and A2, new antibiotics active against anaerobes, produced by Streptomyces cervinus sp. nov.The Journal of Antibiotics, 1982
- Metabolites of microorganisms. 162nd Communication. The crystal and molecular structure of lysolipin IHelvetica Chimica Acta, 1977
- Stoffwechselprodukte von MikroorganismenArchiv für Mikrobiologie, 1975