Synthesis of Functionalized Heteroaromatics: Application to Formal Total Synthesis of Camptothecin

1 March 1997

journal article
letter
Published by Georg Thieme Verlag KG in Synlett

Vol. 1997 (3) , 298-300
https://doi.org/10.1055/s-1997-785

Abstract

The formal total synthesis of camptothecin was achieved via two types of lithiation reactions of pyridine derivatives and a Pd-catalyzed carbonylation of pyridylmethyl methanesulfonates.

Keywords

CAMPTOTHECIN
LITHIATION
6-DICHLOROPYRIDINE
THE PD-CATALYZED CROSS-COUPLING REACTION
THE PD-CATALYZED CARBONYLATION

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