Crural hypertrophy associated with centronuclear myopathy

Abstract
A case of centronuclear myopathy of adult onset with striking hypertrophy of lower limb muscles in a black South African man is described with details of the light microscopic, histochemical and ultrastructural features. The association of hypertrophied muscles with centronuclear myopathy has not been previously reported; this may be a variant condition.

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