Diazepam induces a dissociation between explicit and implicit memory
- 1 October 1989
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 99 (2) , 238-243
- https://doi.org/10.1007/bf00442815
Abstract
The effects of 0.2 mg/kg orally administered diazepam and of a placebo on explicit memory, implicit and knowledge memory were assessed using a free recall task, a word-stem completion task and two category-generation tasks. Twenty four healthy volunteers took part in this double-blind study. Diazepam impaired explicit but not implicit memory. The drug also spared knowledge memory. Explicit memory was linked with the diazepam-induced sedation and with the self-rated affective load of to-be remembered words, but implicit memory was not. The diazepam-induced dissociation between explicit and implicit memory supports the notion of two distinct forms of memory and reproduced the dissociation observed in organic amnesia.Keywords
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