Staining abnormalities of dermal collagen in cats with cutaneous asthenia or acquired skin fragility as demonstrated with Masson's trichrome stain

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Abstract
This retrospective study compared the Masson's trichrome staining properties of collagen in the skin of normal cats and cats with cutaneous asthenia or acquired skin fragility. A Masson's trichrome staining abnormality was seen in all (n= 8) cats with cutaneous asthenia, three of four cats with acquired skin fragility, and none (n= 10) of the normal cats. A grading system developed to classify the intensity and distribution of abnormally stained collagen fibres indicated that cats with cutaneous asthenia had higher scores (P < 0.001) than normal cats. Cats with acquired skin fragility had intermediate scores that were not significantly different from either of the other two groups.