Urinary Excretion of Formiminoglutamic Acid by Human Subjects after Antifolic Acid Therapy1
Open Access
- 1 June 1958
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 37 (6) , 829-832
- https://doi.org/10.1172/jci103671
Abstract
An enzymatic procedure has been applied to the assay of formiminoglutamic acid in the urine of adults and children with a variety of disease states. Urinary formiminoglutamic acid was frequently detected in small quantities, and was markedly increased in children treated with the folic acid antagonist, amethopterin.Keywords
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