Bioreductive alkylation as a trigger for toxic effects of dynemicin
- 1 January 1990
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 31 (11) , 1521-1522
- https://doi.org/10.1016/0040-4039(90)80005-7
Abstract
No abstract availableKeywords
This publication has 7 references indexed in Scilit:
- Coupling of the anthracycline antitumor drug menogaril to 2'-deoxyguanosine through reductive activationJournal of the American Chemical Society, 1989
- The cyclization of calichemicin-esperamicin analogs: a predictive biradicaloid transition stateJournal of the American Chemical Society, 1989
- Experimental modeling of the priming mechanism of the calicheamicin/esperamicin antibiotics: actuation by the addition of intramolecular nucleophiles to the bridgehead double bondJournal of the American Chemical Society, 1989
- Dynemicin A, a novel antibiotic with the anthraquinone and 1,5-diyn-3-ene subunit.The Journal of Antibiotics, 1989
- Synthesis of a remarkably stable bicyclo[7.3.1]diynene esperamicin A1/calicheamicin .gamma. system. Structural requirements for facile formation of a 1,4-diylJournal of the American Chemical Society, 1988
- Cyclic conjugated enediynes related to calicheamicins and esperamicins: calculations, synthesis, and propertiesJournal of the American Chemical Society, 1988
- Naturally occurring quinones as potential bioreductive alkylating agentsMedicinal Research Reviews, 1981