A simplified method for fixation of human and mouse preimplantation embryos which facilitates G-banding and karyotypic analysis
- 1 November 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Human Reproduction
- Vol. 3 (8) , 990-992
- https://doi.org/10.1093/oxfordjournals.humrep.a136829
Abstract
A reliable method for the fixation of large numbers of prelmplantatlon embryos was developed to allow application of routine G-banding methods to preimplantatlon stage embryos. The technique resulted in minimal loss of embryos and was suitable for both 1-cell mouse embryos and multipronuclear human embryos. Application of this method will increase the information gained from chromosome studies of embryonic development.Keywords
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