EXTRADURAL PRESSURE FOLLOWING THE INJECTION OF TWO VOLUMES OF BUPIVACAINE

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Abstract
We investigated the influence of the pressure generated by low lumbar extradural injection of bupivacaine on the development of block in a randomized double-blind study. Thirty patients (aged 17–66 yr) received one of two volumes of 0.75% bupivacaine. Group I (n=15) received 10 ml (75 mg) and group II (n=15) 15 ml (112.5 mg). Injection of the larger volume resulted in a greater pressure at the end of injection, but within 1 min this decayed to the same plateau pressure that was produced by the smaller volume. Mean maximum cephalad spread of block was the same in each group (group I, T9.5; group II, T8.4) and there was no correlation between individual level of block and maximum or plateau extradural pressure, or with patient characteristics.

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