The First Asymmetric Synthesis of (1R,1′S)-1-[1′-(Benzyloxycarbonyl-methylamino)-2′-phenylethyl]oxirane: a Promising Building Block for the Synthesis of Peptide Mimics

Publisher Website
Google Scholar
Abstract
The threo N-methyl oxirane 5 was prepared from (S)-N-methyl phenylalanine by bromoketone reduction or by epoxidation routes. The unexpected stereochemical result of the reduction of bromoketone 7 leading to the threo isomer is discussed.

This publication has 0 references indexed in Scilit: