A Critique of Clinical Equipoise: Therapeutic Misconception in the Ethics of Clinical Trials
Top Cited Papers
- 1 May 2003
- journal article
- Published by JSTOR in Hastings Center Report
- Vol. 33 (3) , 19-28
- https://doi.org/10.2307/3528434
Abstract
A predominant ethical view holds that physician-investigators should conduct their research with therapeutic intent. And since a physician offering a therapy wouldn't prescribe second-rate treatments, the experimental intervention and the best proven therapy should appear equally effective. "Clinical equipoise" is necessary. But this perspective is flawed. The ethics of research and of therapy are fundamentally different, and clinical equipoise should be abandoned.Keywords
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