FIBROUS BODIES IN GROWTH-HORMONE SECRETING ADENOMAS CONTAIN CYTOKERATIN FILAMENTS
- 1 January 1985
- journal article
- research article
- Vol. 109 (6) , 505-508
Abstract
Fibrous bodies in growth hormone-secreting adenomas were studied by immunocytochemistry using an anti-cytokeratin antiserum. Fibrous bodies are a feature of acidophil and chromophobe adenomas and are usually associated with acromegaly. Ultrastructural examination revealed round juxtanuclear filamentous aggregates, composed of 8-nm filaments and other organelles. This study demonstrated that the intermediate filaments of fibrous bodies belong to the cytokeratin class. The etiology and significance of these filamentous aggregates remain obscure.This publication has 13 references indexed in Scilit:
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