Strumal Carcinoid of the Ovary: Ultrastructural Observations and Long-term Follow-up Study

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Abstract
Hart, William R., and Regezi, Joseph A.: Strumal carcinoid of the ovary. Ultrastructural observations and long-term follow-up study. Am J Clin Pathol 69: 356-359, 1978. Herein is reported an ovarian strumal carcinoid in a mature teratoma from a 54-year-old woman. Ultrastructural examination revealed numerous electron-dense intracellular granules, which were interpreted as neurosecretory granules. They corresponded to argyrophil granules observed by light microscopy and were identified within neoplastic cells arranged in both follicular and trabecular patterns. These findings corroborate the contention that the strumal carcinoid itself is a pure neuroendocrine tumor devoid of thyroid follicular epithelium, but do not disprove its possible origin from parafollicular cells of adjacent teratomatous thyroid tissue. There was no recurrence of tumor during the 20½ years the patient was followed.

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