Respiration-dependent efflux of magnesium ions from heart mitochondria
- 15 March 1976
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 154 (3) , 735-742
- https://doi.org/10.1042/bj1540735
Abstract
Energy-linked respiration causes a net movement of Mg2+ between rat heart mitochondria and the ambient medium. When the extramitochondrial concontration of Mg2+ is less that about 2.5 mM the net movement of Mg2+ constitutes an efflux, whereas a net influx of Mg2+ occurs when the external concentration of Mg2+ is greater than this. Both the efflux and the influx are induced to only a very small degree by externally added ATP. Evidence suggests that Pi may be required for the respiration-induced efflux of Mg2+.This publication has 25 references indexed in Scilit:
- Indicators of free magnesium in biological systemsBiochemistry, 1974
- Analysis of the Reactivity of SH-Reagents with the Mitochondrial Phosphate CarrierEuropean Journal of Biochemistry, 1974
- The effect of ruthenium red on Ca2+ transport and respiration in rat liver mitochondriaBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1972
- Intramitochondrial distribution of magnesiumBiochemical and Biophysical Research Communications, 1971
- Correlation Between H+ and Anion Movement in Mitochondria and the Key Role of the Phosphate CarrierEuropean Journal of Biochemistry, 1971
- Control of cation movements in liver mitochondria by a cytoplasmic factorBiochemical and Biophysical Research Communications, 1971
- Specific inhibition of mitochondrial Ca++ transport by ruthenium redBiochemical and Biophysical Research Communications, 1971
- Regulation of mitochondrial metabolism by specific cellular substances. II. The nature of stimulation of mitochondrial glutamate metabolism by a cytoplasmic componentBiochemistry, 1969
- Energy‐Linked Ion Movements in Mitochondrial SystemsPublished by Wiley ,1967
- Efficiency of Oxidative PhosphorylationNature, 1954