Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor.
Open Access
- 1 August 1990
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 265 (22) , 12820-12827
- https://doi.org/10.1016/s0021-9258(19)38233-x
Abstract
No abstract availableThis publication has 62 references indexed in Scilit:
- Thapsigargin, a novel promoter, phosphorylates the epidermal growth factor receptor at threonine 669Biochemical and Biophysical Research Communications, 1988
- Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activityCell, 1987
- PROTEIN SERINE/THREONINE KINASESAnnual Review of Biochemistry, 1987
- Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding.The Journal of cell biology, 1986
- Identification of the sites on rabbit skeletal muscle protein phosphatase inhibitor-2 phosphorylated by casein kinase-IIBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986
- Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanismsCell, 1986
- Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membraneNature, 1984
- Tumor promoter phorbol 12-myristate 13-acetate inhibits mitogen-stimulated Na+/H+ exchange in human epidermoid carcinoma A431 cells.The Journal of cell biology, 1984
- Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.Proceedings of the National Academy of Sciences, 1979
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970