Circulating Antibody Formation in Scorbutic Guinea Pigs
- 1 May 1969
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 98 (1) , 41-44
- https://doi.org/10.1093/jn/98.1.41
Abstract
Severe scurvy was induced in young guinea pigs by feeding a highly purified ascorbic acid-deficient diet. After immunization with diphtheria toxoid, no deleterious effects on primary or secondary circulating antibody formation were observed in these scorbutic guinea pigs. A reduction in the early, Arthus-type, dermal hypersensitivity observed in the immunized scorbutic guinea pigs did not appear to be immunological in nature.Keywords
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