Creatinine, urea and uric acid in amniotic fluid, maternal and umbilical cord blood at delivery
- 1 January 1975
- journal article
- research article
- Published by Springer Nature in Archiv für Gynäkologie
- Vol. 220 (1) , 65-72
- https://doi.org/10.1007/bf00673149
Abstract
Amniotic fluid, maternal vein serum and umbilical cord serum were obtained almost simultaneously from 31 women after an uneventful course of pregnancy. Specimens of amniotic fluid contaminated by blood or meconium were excluded. Creatinine, urea and uric acid were measured by autoanalyser techniques. The concentrations of creatinine, urea and uric acid in amniotic fluid were significantly higher when compared with the levels in maternal vein serum or umbilical cord serum. Between maternal and umbilical cord serum there were only small or no differences. The linear correlations of creatinine, urea and uric acid between maternal and umbilical cord serum were greater than those between amniotic fluid and maternal serum or amniotic fluid and cord serum. It is suggested that the high levels of creatinine, urea and uric acid in amniotic fluid are primarily determined by fetal urine. In 31 Fällen wurde nach normaler Schwangerschaft parallel Fruchtwasser, mütterliches Venenblut und Nabelschnurblut gewonnen. Fruchtwasserproben, die durch Blut oder Mekonium kontaminiert waren, wurden verworfen. Kreatinin, Harnstoff und Harnsäure wurden mit dem Autoanalyzer bestimmt. Die Kreatinin-, Harnstoff- und Harnsäurekonzentrationen im Fruchtwasser lagen signifikant höher als die Spiegel im mütterlichen Venenblut- oder Nabelschnurserum. Zwischen mütterlichem Serum und Nabelschnurserum fanden sich geringe oder keine Unterschiede. Die linearen Korrelationen für Kreatinin, Harnstoff und Harnsäure zwischen mütterlichem Serum und Nabelschnurserum waren größer als die zwischen Fruchtwasser und mütterlichem Serum oder Fruchtwasser und Nabelschnurserum. Es ist anzunehmen, daß die hohen Kreatinin-, Harnstoff- und Harnsäurespiegel im Fruchtwasser in erster Linie durch den fetalen Urin zustande kommen.Keywords
This publication has 9 references indexed in Scilit:
- Composition of the amniotic fluid and maternal serum in pregnancyAmerican Journal of Obstetrics and Gynecology, 1974
- AMNIOTIC FLUID URIC ACID LEVELS IN THE MATURING FETUSBJOG: An International Journal of Obstetrics and Gynaecology, 1972
- Amniotic Fluid: The Value of Prenatal AnalysisPostgraduate Medicine, 1972
- COMPOSITION OF AMNIOTIC FLUID AND MATERNAL BLOOD THROUGH PREGNANCYBJOG: An International Journal of Obstetrics and Gynaecology, 1971
- FETAL FACTORS INFLUENCING THE VOLUME AND COMPOSITION OF LIQUOR AMNII*BJOG: An International Journal of Obstetrics and Gynaecology, 1970
- Creatinine, uric acid, and electrolytes in amniotic fluidAmerican Journal of Obstetrics and Gynecology, 1970
- CHANGES IN THE ELECTROLYTES, UREA AND OSMOLALITY OF THE AMNIOTIC FLUID WITH ADVANCING PREGNANCY*BJOG: An International Journal of Obstetrics and Gynaecology, 1969
- Amniotic fluid creatinineAmerican Journal of Obstetrics and Gynecology, 1967
- COMPOSITION OF AMNIOTIC FLUIDClinical Obstetrics and Gynecology, 1966