MORPHOLOGIC SIMILARITIES OF HUMAN AND CANINE GLOBOID LEUKODYSTROPHY - THIN SECTION AND FREEZE-FRACTURE STUDIES
- 1 January 1976
- journal article
- research article
- Vol. 85 (1) , 99-+
Abstract
Human and canine globoid leukodystrophy were indistinguishable morphologically [by light microscopy and EM]. Both had characteristic deposits with polygonal cross-sectional profiles in addition to twisted ribbon-like structures. The specificity of the deposits was emphasized, and their laminated nature was corroborated by freeze-fracture studies. Their apparently hollow profiles in cross section may be produced by the tight arrangement of the bilayers that prevent penetration of the stain.This publication has 17 references indexed in Scilit:
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