Müllerian adenosarcoma of the uterine cervix with heterologous elements: a clinicopathological and electron microscopic study

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Abstract
Summary A Müllerian adenosarcoma of the uterine cervix in a 14 year old girl was studied by light and electron microscopy. The tumour was composed of a stromal sarcoma, benign glands of endometrial type and heterologous elements, such as rhabdomyoblasts, lipoblasts and mature striated muscle cells. On electron microscopic study stromal cells and rhabdomyoblasts in different stages of maturation comprised the major part of the tumour. The less aggressive behaviour of the Müllerian adenosarcoma in comparison to other uterine sarcomas and the benign appearing glandular element are distinctive features of this tumour. Stages of maturation of muscle cells and the origin of the benign element are discussed. An attempt was made to explain the less aggressive nature of the tumour.