HLA Dependence of Sensitivity to Nickel and Chromium
- 1 March 1981
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 17 (3) , 261-264
- https://doi.org/10.1111/j.1399-0039.1981.tb00699.x
Abstract
A group of patients with cutaneous sensitivity was compared with another group with cement dermatitis who showed sensitivity to chromate. HLA typing for A and B locus antigens demonstrated a 29% incidence of B21 in the nickel sensitive group (control population 4.9%) and the antigen was not found in 16 patients with chromium sensitivity. It is suggested that this may represent a hapten specific HLA dependent immune response in man.This publication has 3 references indexed in Scilit:
- HLA-Antigens and Contact HypersensitivityJournal of Investigative Dermatology, 1979
- The Immune Response Genes of the Major Histocompatibility ComplexImmunological Reviews, 1978
- HL-A TYPES IN ATOPIC DERMATITISThe Lancet, 1973