Comparison of Blood Serum Iodine Levels with use of Iodoplex and Povidone Iodine Ointment

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Abstract
Concentrations of I were assayed in burn patients, who were covered with Iodoplex ointment up to 30% of their body surface. The I levels in the serum were in linear proportion to the area treated with an increase of 30 .mu.g I per 100 ml of serum for 1% of TBSA [total body surface area]. The maximal levels were reached within 24 h of applying the Iodoplex ointment, and decreased quickly following its discontinuation. Concentrations of the I were much lower than those found after treatment with povidone iodine, a fact which indicates that using Iodoplex in second-degree burns and donor sites entails fewer possible complications due to high levels of I in the serum than with povidone iodine.