Role of Genes and Environments for Explaining Alzheimer Disease
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Open Access
- 1 February 2006
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 63 (2) , 168-174
- https://doi.org/10.1001/archpsyc.63.2.168
Abstract
Alzheimer disease (AD) is a major public health issue, with prevalence of dementia from 6% to 10% in adults aged 65 years and older, of which approximately two thirds of the cases are AD.1 With the population of older adults increasing, the number of cases will increase. Understanding the risk factors for AD can direct investigations of ways to reduce disease occurrence.2 A number of genetic risk factors have been identified, but only a small proportion of AD cases can be explained by specific gene mutations.1 Empirical support for specific environmental risk or protective factors has often been inconsistent.1,3Keywords
This publication has 1 reference indexed in Scilit:
- Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)Published by American Psychiatric Association Publishing ,2000