Effects of [Asu1,7]-eel calcitonin on gastric somatostatin and gastrin release.
Open Access
- 1 February 1980
- Vol. 21 (2) , 94-97
- https://doi.org/10.1136/gut.21.2.94
Abstract
Effects of [Asu1,7]-eel calcitonin on gastric somatostatin and gastrin secretion were studied by using the isolated perfused rat stomach. [Asu1,7]-eel calcitonin (10(-9)--10(-7)M) caused a simultaneous dose-dependent increase of gastric somatostatin release and decrease of gastrin secretion, with a significant correlation between these two. The demonstration of calcitonin stimulation of gastric somatostatin release raises the possibility of somatostatin-mediated suppression of gastrin secretion by calcitonin.Keywords
This publication has 25 references indexed in Scilit:
- Pancreatic and Gastric Somatostatin Release in Response to Intragastric and Intraduodenal Nutrients and HCl in the DogJournal of Clinical Investigation, 1978
- Gastrointestinal somatostatin: extraction and radioimmunoassay in different species.Gut, 1978
- Somatostatin release from isolated perfused rat stomachBiochemical and Biophysical Research Communications, 1978
- Inhibition by somatostatin (growth-hormone release-inhibiting hormone, GH-RIH) of gastric acid and pepsin and G-cell release of gastrin.Gut, 1978
- Stability of [Asu1,7]-eel calcitonin and eel calcitonin in vitro and in vivo.Endocrinologia Japonica, 1977
- Role of Endogeneous Calcitonin in the Secretion of Gastrin and Gastric Acid in RatsHormone and Metabolic Research, 1977
- Nuclear pores in the spermatozoon of the ratCellular and Molecular Life Sciences, 1976
- Somatostatin: Abundance of Immunoreactive Hormone in Rat Stomach and PancreasScience, 1975
- INHIBITION OF GASTRIN AND GASTRIC-ACID SECRETION BY GROWTH-HORMONE RELEASE-INHIBITING HORMONEThe Lancet, 1974
- Das Druckprofil im unteren Ösophagussphinkter beim Menschen und seine Beeinflussung durch Gastrin, Calcitonin und GlucagonDeutsche Medizinische Wochenschrift (1946), 1973