Ionic mechanism for the photoreceptor potential of the retina of Bufo marinus

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Abstract
1. Membrane potentials were recorded from single rods in the isolated retina of Bufo marinus while the ionic composition of the extracellular medium was rapidly changed. Substitution of 2 mM aspartate- for Cl- produced a prompt depolarization of horizontal cells, but no modification of either resting potential or response to light in receptor cells. This implies that feed-back from horizontal cells to receptor cells was not active.

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