Evolution of Neovascularization in Sickle Cell Retinopathy
- 1 September 1977
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)
- Vol. 95 (9) , 1543-1552
- https://doi.org/10.1001/archopht.1977.04450090065005
Abstract
• With prospective observations we have documented by fluorescein angiography the development of retinal neovascularization in the eyes of patients with sickle cell-hemoglobin C disease (hemoglobin SC). In each patient, arteriolarvenular (AV) anastomoses occurred before the development of neovascular sea fans. To our knowledge, this report constitutes the first such documentation in the literature. New sea fans from AV anastomoses appeared throughout an average interval of 18 months (range, 8 to 36 months) in approximately 21% of young adutls with hemoglobin SC. Each year approximately 14% of young patients with hemoglobin SC may develop retinal neovascularization. (Arch Ophthalmol95:1543-1552, 1977)This publication has 7 references indexed in Scilit:
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- The progression of sickle cell eye disease in JamaicaDocumenta Ophthalmologica, 1975
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- Classification and Pathogenesis of Proliferative Sickle RetinopathyAmerican Journal of Ophthalmology, 1971
- Sickle-Cell Hemoglobin and Its Relation to Fundus AbnormalityArchives of Ophthalmology (1950), 1966