COMPARATIVE CALORIGENIC ACTION OF NORMAL AND PATHO-LOGICAL THYROID GLANDS ADMINISTERED IN EQUI-THYROXINE DOSES
Open Access
- 1 September 1935
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 14 (5) , 619-631
- https://doi.org/10.1172/jci100711
Abstract
Em-ploying guinea pigs as test animals the calorigenic ac-tion of thyroid preparations obtained from normal and pathologic human subjects and normal animals was found to be proportional to the thyroxine content as detd. chemically and not to the total I. No evidence was obtained in favor of the existence of an abnormal substance contributing to the toxicity of pathologic glands.Keywords
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