Selective IgA Deficiency in Australian Blood Donors
- 1 August 1980
- journal article
- research article
- Published by Wiley in Australian and New Zealand Journal of Medicine
- Vol. 10 (4) , 410-413
- https://doi.org/10.1111/j.1445-5994.1980.tb04091.x
Abstract
Selective serum Ig[immunoglobulin]A deficiency (defined as a serum IgA level less than 50 mg/l) was detected in 14 of 6191 [human] Australian blood donors screened by double diffusion analysis of serum specimens in agarose. This prevalence rate of 0.23% (1 in 442) is the same as that found in blood donors in Sweden, but is higher than rates found in blood donors in France (0.05%), Norway (0.08%), USA (0.15%), England (0.19%) and Finland (0.20%). Antibodies to human IgA were detected in the serum of 3 of 11 blood donors with selective IgA deficiency (27%). There was no evidence in the present study of blood transfusion reactions from these anti-IgA antibodies when they were transfused into recipients.This publication has 21 references indexed in Scilit:
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