Reverse Ventilation-Perfusion Mismatch

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Abstract
Patients having lobar airway obstruction or consolidation usually have decreases of both ventilation and perfusion on lung scans. Three patients are reported in whom hypoxic vasoconstriction was apparently incomplete, resulting in a reversed ventilation-perfusion mismatch. Perfusion of the hypoxic lobe on the radionuclide scan was associated with metabolic alkalosis, pulmonary venous and pulmonary arterial hypertension in these patients.