Free fatty acids trigger apoptosis and inhibit cell cycle progression in human vascular endothelial cells
Open Access
- 3 November 2003
- journal article
- fj express-summarie
- Published by Wiley in The FASEB Journal
- Vol. 18 (1) , 146-148
- https://doi.org/10.1096/fj.03-0301fje
Abstract
Plasma free fatty acid (FFA) concentrations are increased in states of insulin resistance and impair endothelial function. Because the underlying mechanisms are largely unknown, we examined selected,...Keywords
This publication has 57 references indexed in Scilit:
- The endothelium as a metabolic and endocrine organ: its relation with insulin resistanceExperimental and Clinical Endocrinology & Diabetes, 2001
- Endothelial Apoptosis Induced by Oxidative Stress Through Activation of NF-κBHypertension, 2001
- Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and DeathScience, 2001
- Levamisole induced apoptosis in cultured vascular endothelial cellsBritish Journal of Pharmacology, 2000
- The effects of free fatty acids on glucose transport and phosphorylation in human skeletal muscleCurrent Opinion in Endocrinology, Diabetes and Obesity, 2000
- High free fatty acid concentration: an independent risk factor for hypertension in the Paris Prospective StudyInternational Journal of Epidemiology, 1998
- Regulation of Tight Junction Permeability and Occludin Expression by Polyunsaturated Fatty AcidsBiochemical and Biophysical Research Communications, 1998
- Oleic Acid Inhibits Endothelial Nitric Oxide Synthase by a Protein Kinase C–Independent MechanismHypertension, 1995
- The retinoblastoma protein and cell cycle controlCell, 1995
- Mechanisms of fatty acid-induced inhibition of glucose uptake.Journal of Clinical Investigation, 1994