X-Ray Microanalysis of the Element Content in the Hearts of Mice Treated with Digoxin
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in Cardiology
- Vol. 75 (5) , 344-347
- https://doi.org/10.1159/000174397
Abstract
The element content was detected by X-ray microanalysis in the hearts of mice treated with daily doses of 0.075 µg digoxin for 12 days and compared with that of controls. Statistically significant differences were found for K and S, which were lower, and for P, which was higher following treatment with digoxin. In the sera of the treated mice Mg was slightly lower, whereas Ca and K levels were found to be elevated in comparison with those of nontreated animals. A possible explanation for these findings is discussed.This publication has 3 references indexed in Scilit:
- Frequency of hypomagnesemia in hospitalized patients receiving digitalisArchives of internal medicine (1960), 1985
- Effects of chronic digoxin treatment on cardiac function, electrolytes, and sarcolemmal ATPase in the canine failing heart due to chronic mitral regurgitationAmerican Heart Journal, 1984
- Correlation between manifestations of digoxin toxicity and serum digoxin, calcium, potassium, and magnesium concentrations and arterial pH.BMJ, 1983