Effects of Chrysaora quinquecirrha (Sea Nettle) Toxin on the Rat Cardiovascular System

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Abstract
Sea nettle (Chrysaora quinquecirrha) tentacles inflict cutaneous damage on many animals, including man. The cardiovascular action of the nettle toxin was investigated to determine whether this agent was capable of injuring tissues other than skin. Cardiac conduction abnormalities and ischemic electrocardiographic changes occurred in rats shortly after intravenous injections of the nettle toxin. Large doses of toxin produced a prompt increase in arterial blood pressure. These results support the premise that the nettle's sting, which clinically injures human skin, might affect other tissues if an adequate dosage were administered.

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