σ-Complexes as biophysical and biochemical probes. Part II. Transformations of σ-complex intermediates from reaction of 4-nitrobenzofuroxan and methoxide ion
- 1 August 1977
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 55 (15) , 2852-2855
- https://doi.org/10.1139/v77-396
Abstract
Reaction of 4-nitrobenzofuroxan with methoxide ion in methanolic dimethyl sulfoxide solution gives rise to 7-hydroxy-4-nitrobenzofurazan (as the anion) and 7-methoxy-4-nitrobenzofurazan (as the methoxide C-7 adduct); the proposed reaction mechanism invokes the formation of several transient intermediates. The results bear on the postulated mechanism for the antileukemic activity of 4-nitrobenzofuroxan.This publication has 1 reference indexed in Scilit:
- σ-Complexes as biochemical probes. Part 1. σ-Complex formation by 7-methoxy-4-nitrobenzofurazan 1-oxideJournal of the Chemical Society, Perkin Transactions 1, 1977